My twitter life as @bph has become much richer again and much more conversational, once I un-followed a few hundred people. I now follow about 800 down from 1400. Interestingly enough my own follower count stayed stable at ~1700. So don't be afraid to shed some of the less relevant noise you have to deal with.

Amplify’d from blog.feedblitz.com

The thing is, my attention is limited. I need to focus it on clients, prospects, industry news and the non-work stuff that floats my boat. So I am very, very discriminatory (in that, I make informed choices) about whom I follow, just as I choose carefully which blogs to subscribe to. There's more than enough noise in my Twitter stream as it is with the few people I do give my attention to; I am therefore very careful about whom I add. I also don't unfollow very much, precisely because I take care about the people I add in the first place. I'm not saying I'm a guru or super special and that if I follow your Twitter stream then somehow you are extra blessed; I'm just saying that when I do follow it's interesting enough for me to keep up with. That's it. Nothing more. Read more at blog.feedblitz.com